RESUMO
OBJECTIVE: To describe clinical characteristics, hormonal profile and body composition of obese men in preoperative of bariatric surgery. METHODS: Cross-sectional, population-based study. Patients evaluated from June 2019 to December 2021 in two obesity referral centers. Patients underwent clinical evaluation, androgen deficiency screening using ADAM (Androgen Deficiency in the Aging Male questionnaire), hormonal profile and body composition assessment through body mass index (BMI), body fat percentage (FM-%) and mass (FM-kg) measured by electrical bioimpedance and dual energy X-ray absorptiometry. To characterize hypogonadism, two cut-off points were considered: TT <264ng/dL and TT <164ng/dL. RESULTS: Thirty patients were included, mean age 35.6±8.8 years, mean weight 129.4±14.0 kg and mean BMI 42.3±4.7 kg/m2. Dyslipidemia was the most prevalent comorbidity. Considering TT <264ng/dL, 22 patients (73%) had hypogonadism. The mean TT in hypogonadal men was 198.9+68.7 ng/dL and in eugonadal men 357.0+59.5ng/dl (p<0.001). Using TT <164 ng/dL, 7 patients (23%) had hypogonadism. The mean TT in hypogonadal patients was 116.6+28.9 ng/dL and in eugonadal patients 279.0+75.0 ng/dL (p<0.001). In ADAM, 93.3% had positive screening, with no significant difference between groups. There was no statistically significant difference in body composition between groups when using TT<264ng/dL as the hypogonadism cutoff. Considering hypogonadism TT<164ng/dL, hypogonadal patients had significantly higher values of weight (139.0x126.5kg p=0.036), BMI (46.1x41.2kg/m2 p=0.014), FM-% (48.0x42.8% p=0.010) and FM-kg (66.3x53.9kg p=0.007) than eugonadal patients. CONCLUSION: Hypogonadism was identified in at least 23% of patients. Considering TT below the lower limit of normality for characterization of hypogonadism, we identified a significant worsening in body composition parameters.
